Lead compound is a compound with certain biological activity and chemical structure obtained by various ways and means for further structural modification and optimization, which is the starting point of modern new drug research.

Lead compound optimization is the process of optimizing other defective properties while maintaining some of the excellent properties of the lead compound. The goal of optimizing a lead compound is to produce one or more preclinical candidate compounds. PharmaResources can provide a variety of services such as pharmacochemical research, computer aided drug design, compound synthesis and scale-up.